The article you requested is
Is Statin Use Safe in Individuals With Psychotic Disorders?
J Clin Psychiatry 2008;69:1499-1499 [letter]
Copyright 2008 Physicians Postgraduate Press, Inc.
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Letter to the Editor
>Sir: Individuals with schizophrenia and other serious mental
illnesses have a mortality rate at least 2 times as high as those
without psychotic disorders, with the excess mortality largely
attributed to higher rates of death from cardiovascular disease.
Wider use of cholesterol-lowering drugs (statins) to reduce
cardiovascular risk in this setting has been suggested. However,
widespread use of statin drugs in individuals with psychotic
disorders may raise some concerns.
Accumulating evidence suggests a relation between low
cholesterol and violence, aggression, and hostility, notwithstanding
that the biological basis for attributing causality for
behavioral disorders and hypocholesterolemia is not clear.