The article you requested is
A Polymorphism in the Angiotensin-Converting Enzyme Gene Is Associated With Smoking Behaviour
J Clin Psychiatry 2008;69:1983-1985 [letter]
Copyright 2008 Physicians Postgraduate Press, Inc.
To view this item, select one of the options below.
Purchase this PDF for $40
If you are not a paid subscriber, you may purchase the PDF.
(You'll need the free Adobe Acrobat Reader.)
Receive immediate full-text access to JCP. You can subscribe to JCP print + online for $166 individual.
If you are a paid subscriber to JCP and do not yet have a username and password, activate your subscription now.
As a paid subscriber who has activated your subscription, you have access to the HTML and PDF versions of this item.
Still can't log in? Contact the Circulation Department at 1-800-489-1001 x4 or send an email
Letter to the Editor
Sir: Nicotine abuse and dependence is a complex addictive
disorder with a pronounced genetic background. In addition, it
is one of the strongest risk factors for cardiovascular disorders
(CVD). It has been extensively discussed whether the known
high comorbidity between CVD and major depressive disorder
(MDD) is more likely determined by biological, such as genetic,
variables or by behavioral changes caused by depression,
which in turn enhance cardiovascular risks. Functional polymorphisms
of the angiotensin-converting enzyme (ACE) gene
are susceptibility factors for MDD.