10006089 J Clin Psychiatry / Document Archive

Psychiatrist.com Home    Keyword Search

Close [X]

Search Our Sites

Enter search terms below (keywords, titles, authors, or subjects). Then select a category to search and press the Search button. All words are assumed to be required. To search for an exact phrase, put it in quotes. To exclude a term, precede it with a minus sign (-).

Keyword search:

Choose a category:

Choosing the appropriate category will greatly improve your chances of finding the best match.

All files at our sites: J Clin Psychiatry, Primary Care Companion, CME Institute, and MedFair

Search materials from our journals:

Abstracts from The Journal of Clinical Psychiatry, 1996–present, both regular issues and supplements

PDFs of the full text of The Journal of Clinical Psychiatry, 1996–present, both regular issues and supplements (Net Society Platinum [paid subscribers])

PDFs of the full text of The Primary Care Companion to The Journal of Clinical Psychiatry, 1999–present

Search CME offerings:

CME Institute, including CME from journals , supplements, and Web activities for instant CME credit (Net Society Gold [registered users]); also includes information about our CME program

CME activities from regular issues of The Journal of Clinical Psychiatry (Net Society Gold [registered users])

CME Supplements from The Journal of Clinical Psychiatry (Net Society Gold [registered users])


The article you requested is

Individualized Treatment for Outpatients Withdrawing From Alcohol

J Clin Psychiatry 1998;59:289-293
Copyright 1998 Physicians Postgraduate Press, Inc.

To view this item, select one of the options below.

    1. Purchase this PDF for $40
      If you are not a paid subscriber, you may purchase the PDF.
      (You'll need the free Adobe Acrobat Reader.)
    2. Subscribe
      Receive immediate full-text access to JCP. You can subscribe to JCP print + online for $166 individual.
      JCP's 75th AnniversaryCelebrate!
      Celebrate JCP's 75th Anniversary with a special online-only subscription price of $75.
    1. Activate
      If you are a paid subscriber to JCP and do not yet have a username and password, activate your subscription now.
    2. Sign in
      As a paid subscriber who has activated your subscription, you have access to the HTML and PDF versions of this item.
  1. Did you forget your password?

Still can't log in? Contact the Circulation Department at 1-800-489-1001 x4 or send an email


Background: This prospective study addressed the applicability of symptom-triggered detoxification to the outpatient setting.

Method: We studied 108 alcohol-dependent patients consecutively enrolled in an outpatient detoxification program between January 17, 1995, and October 17, 1995. The diagnosis was confirmed by verifying, through chart review, that patients met DSM-IV criteria for alcohol dependence. Patients were prescribed chlordiazepoxide according to a symptom-triggered detoxification protocol that utilized a standardized withdrawal scale. We compiled outcome data by reviewing the chart and the computerized medical record. Outcome was operationally defined to include completion of outpatient detoxification as well as outcome measures that were used in earlier studies of symptom-triggered detoxification in the hospital setting.

Results: Chlordiazepoxide was administered to only 41 patients (38%), yet 92 (85%) of the 108 enrolled successfully completed outpatient detoxification without medical complications. The patients who took chlordiazepoxide received a mean±SD total of 167.2±123.5 mg administered over 2.7±1.4 days. Mean g-glutamyltransferase levels were higher for the group of patients who subsequently received chlordiazepoxide (132.8±312.1 IU/L compared with 56±80.3 IU/L; Wilcoxon rank sum test, t=2600.5, p<.01).

Conclusion: This study is the first to support the feasibility of symptom-triggered detoxification from alcohol in an outpatient setting. Our completion rate compared favorably with completion rates from previous studies of outpatient detoxification from alcohol using fixed-dose schedules. The percentage of patients receiving chlordiazepoxide and mean total amount of chlordiazepoxide administered in our study were also comparable to results from previous studies of symptom-triggered detoxification with hospitalized patients.