The article you requested is
Brainstorms: "Awakening" From Schizophrenia: Intramolecular Polypharmacy and the Atypical Antipsychotics
J Clin Psychiatry 1997;58:381-382
Copyright 1997 Physicians Postgraduate Press, Inc.
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Is the ideal antipsychotic a
soloist or a member of a
large ensemble? The earliest antipsychotic melody of D2 receptor
antagonism was embedded in a cacophony
of jackhammering antihistamines,
and droning α-antagonists. This molecular
noise is somewhat filtered by
high-potency antipsychotics, but the
emerging dopamine antagonist theme
song is too loud, grating on nerves, especially