The article you requested is
Cytochrome P450 2D6 Polymorphism and Its Impact on Decision-Making in Psychopharmacotherapy: Finding the Right Way in an Ultrarapid Metabolizing Patient
J Clin Psychiatry 2011;72(11):1465-1467
Copyright 2011 Physicians Postgraduate Press, Inc.
To view this item, select one of the options below.
Purchase this PDF for $40
If you are not a paid subscriber, you may purchase the PDF.
(You'll need the free Adobe Acrobat Reader.)
Receive immediate full-text access to JCP. You can subscribe to JCP print + online for $166 individual.
If you are a paid subscriber to JCP and do not yet have a username and password, activate your subscription now.
As a paid subscriber who has activated your subscription, you have access to the HTML and PDF versions of this item.
Still can't log in? Contact the Circulation Department at 1-800-489-1001 x4 or send an email
Because this piece does not have an abstract, we have provided for your benefit the first 3 sentences of the full text.
The cytochrome P450 (CYP) superfamily represents the most important phase I drug metabolizing enzyme system. Genetic mutations play an important role in the activity especially of CYP2D6. Genetic polymorphisms within CYPs affect the metabolism of drugs as substrates for the particular enzymes, resulting in variations in plasma levels of the drugs, differences in drug response, or altered risk for adverse effects.