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Drs Sanchez-Gistau and Castro-Fornieles Reply
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To the Editor: We appreciate the interest of Dr Patil and colleagues in our study about predictors of suicide attempt in early-onset, first episode psychoses.
Dr Patil and colleagues raise concerns about a number of methodological issues of the study. First, with regard to the suitability of the Positive and Negative Syndrome Scale (PANSS) in measuring psychotic symptoms in adolescents, many studies have used the PANSS for the assessment of psychotic symptoms in early-onset schizophrenia (see recent reviews by Schimmelmann et al and by Clemmensen et al).
Second, the Children’s Depression Rating Scale (CDRS), which is derived from the HDRS Hamilton Depression Rating Scale (HDRS),was developed to assess depressive symptoms in children aged 6 to 12 years.